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Edge: a framework for developing collective understanding Awaiting Funder
Feb. 23, 2016 —
We propose to create a mobile application for the Life Sciences, targeting non-technical users, that will provide candidate explanations for relationships between pairs of concepts based on information harvested dynamically from the Web.
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Thinklab: A platform for open review of research grant proposals Awaiting Funder
Feb. 15, 2016 —
Thinklab is a platform that facilitates open review of research grant proposals, and a highly collaborative version of open notebook science. We're creating Thinklab because we believe the interests of science and society are best served if the entire scientific process is open — not just the sof...
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Predicting Bcr-Abl targets using a hybrid information extraction system Awaiting Funder
Jan. 18, 2016 —
A graduate student fellowship research proposal to identify novel Bcr-Abl targets using a literature based approach employing crowdsourcing and machine learning.
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Pathways4Life: Crowdsourcing Pathway Modeling from Published Figures Awaiting Funder
June 9, 2015 —
A wealth of novel pathway information is trapped in published figures. This information, if properly modeled would be immensely useful for analyzing and interpreting large-scale omics datasets. Aligned with the broader BD2K initiative, this proposal sets out to transform the wealth of information...
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Rephetio: Repurposing drugs on a hetnet Daniel Himmelstein, Antoine Lizee, Chrissy Hessler, Leo Brueggeman, Sabrina Chen, Dexter Hadley, Ari Green, Pouya Khankhanian, Sergio Baranzini
Report published
Welcome to project Rephetio. We aim to predict the probability that a given approved small molecule will treat a given complex disease. First, we construct a hetnet for drug repurposing. The network integrates 29 public resources and contains 47 thousand nodes (of 11 types) and 2.3 million edges ...
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