Discussion

Subject Last comment Time Views Status
3
Hosting Hetionet in the cloud: creating a public Neo4j instance Daniel Himmelstein May 17, 2017 288
15
Tracking project reuse, citation, and publicity Daniel Himmelstein May 2, 2017 209 Open
9
Using the neo4j graph database for hetnets Daniel Himmelstein April 27, 2017 655 In Progress
46
Report Review: Rephetio: Repurposing drugs on a hetnet Daniel Himmelstein April 10, 2017 136
6
Our hetnet edge prediction methodology: the modeling framework for Project Rephetio Daniel Himmelstein March 13, 2017 125 Open
5
Measuring user contribution and content creation Daniel Himmelstein Feb. 8, 2017 85 In Progress
6
One network to rule them all Daniel Himmelstein Feb. 4, 2017 322 Completed
16
Integrating resources with disparate licensing into an open network Daniel Himmelstein Feb. 2, 2017 517 In Progress
3
Why we predicted ictogenic tricyclic compounds treat epilepsy? Daniel Himmelstein March 10, 2017 31
14
Visualizing the top epilepsy predictions in Cytoscape Daniel Himmelstein Jan. 31, 2017 94
13
Using Entrez Gene as our gene vocabulary Daniel Himmelstein Jan. 26, 2017 265 Completed
14
Brainstorming future directions for Hetionet Alex Ratner Jan. 18, 2017 151 Open
11
Prediction in epilepsy Daniel Himmelstein Jan. 10, 2017 132
3
Decomposing predictions into their network support Daniel Himmelstein Dec. 23, 2016 30
3
Decomposing the DWPC to assess intermediate node or edge contributions Daniel Himmelstein Dec. 23, 2016 21
29
Incorporating DrugCentral data in our network Mike Gilson Dec. 7, 2016 174 Completed
11
STARGEO: expression signatures for disease using crowdsourced GEO annotation Daniel Himmelstein Nov. 30, 2016 358 Completed
4
Evaluation framework Daniel Himmelstein Nov. 25, 2016 75 Open
7
Mining knowledge from MEDLINE articles and their indexed MeSH terms Daniel Himmelstein Nov. 20, 2016 280 Completed
5
Assessing the informativeness of features Daniel Himmelstein Nov. 4, 2016 113 Open
9
Describing Hetionet v1.0 through visualization and statistics Casey Greene Oct. 18, 2016 224 Open
17
Predictions of whether a compound treats a disease Pouya Khankhanian Oct. 16, 2016 330 Open
9
Unifying disease vocabularies Daniel Himmelstein Sept. 22, 2016 313 Completed
6
Exploring the power of Hetionet: a Cypher query depot Daniel Himmelstein Aug. 31, 2016 160
5
Disease Ontology feature requests Daniel Himmelstein Aug. 10, 2016 144 Completed
11
Sounding the alarm on DrugBank’s new license and terms of use Daniel Himmelstein June 24, 2016 552 Completed
1
Edge dropout contamination in hetnet edge prediction Daniel Himmelstein May 16, 2016 37
2
Introducing the Residual Degree Weighted Path Count (R-DWPC) Daniel Himmelstein May 16, 2016 67
2
Cataloging drug–disease therapies in the ClinicalTrials.gov database Daniel Himmelstein May 8, 2016 121 Completed
5
Computing standardized logistic regression coefficients Antoine Lizee May 2, 2016 1615 Open
8
Data nomenclature: naming and abbreviating our network types Daniel Himmelstein April 18, 2016 164 Completed
8
Suggestions for additional information types? Daniel Himmelstein April 16, 2016 165 Open
6
Transforming DWPCs for hetnet edge prediction Daniel Himmelstein April 16, 2016 75 In Progress
8
Estimating the complexity of hetnet traversal Daniel Himmelstein April 16, 2016 72 Completed
2
Network Edge Prediction: Estimating the prior Daniel Himmelstein April 15, 2016 78 In Progress
4
Network Edge Prediction: how to deal with self-testing Daniel Himmelstein April 14, 2016 80 In Progress
11
Creating a catalog of protein interactions Daniel Himmelstein April 11, 2016 181 Completed
26
How should we construct a catalog of drug indications? Daniel Himmelstein April 10, 2016 893 Completed
8
Calculating genomic windows for GWAS lead SNPs Greg Way April 8, 2016 704 Deferred
3
MSigDB licensing Daniel Himmelstein April 3, 2016 195 Completed
11
Adding pathway resources to your network Daniel Himmelstein April 2, 2016 153 Completed
2
The ADEPTUS resource for expression signatures of disease Daniel Himmelstein March 31, 2016 131 Completed
2
Announcing PharmacotherapyDB: the Open Catalog of Drug Therapies for Disease Daniel Himmelstein March 15, 2016 306 Completed
16
Expert curation of our indication catalog for disease-modifying treatments Pouya Khankhanian March 14, 2016 261 Completed
1
Assessing the imputation quality of gene expression in LINCS L1000 Daniel Himmelstein March 11, 2016 198 Completed
2
Assessing the effectiveness of our hetnet permutations Daniel Himmelstein March 11, 2016 76 Completed
5
Positive correlations between knockdown and overexpression profiles from LINCS L1000 Daniel Himmelstein March 9, 2016 268 Open
14
Workshop to analyze LINCS data for the Systems Pharmacology course at UCSF Daniel Himmelstein March 9, 2016 183 Completed
8
Processing Bgee for tissue-specific gene presence and over/under-expression Daniel Himmelstein March 8, 2016 139 Completed
7
Computing consensus transcriptional profiles for LINCS L1000 perturbations Daniel Himmelstein March 7, 2016 679 Completed
8
UniChem Mapping to LINCS Small Molecules Daniel Himmelstein March 7, 2016 450 Completed
6
Renaming ‘heterogeneous networks’ to a more concise and catchy term Daniel Himmelstein Jan. 28, 2016 199 Completed
2
Licensing neo4j Daniel Himmelstein Jan. 11, 2016 318 In Progress
2
Permuting hetnets and implementing randomized edge swaps in cypher Daniel Himmelstein Jan. 6, 2016 112 Deferred
4
Path exclusion conditions Daniel Himmelstein Dec. 21, 2015 331 In Progress
6
Python for the modern biodata scientist Daniel Himmelstein Dec. 2, 2015 986 Open
3
Incomplete Interactome licensing Daniel Himmelstein Nov. 23, 2015 118 Completed
6
Integrating drug target information from BindingDB Daniel Himmelstein Nov. 19, 2015 297 Completed
11
Tissue-specific gene expression resources Daniel Himmelstein Nov. 4, 2015 823 Completed
2
LINCS L1000 licensing Daniel Himmelstein Oct. 19, 2015 387 Completed
15
Processing GTEx for tissue-specific gene expression Frederic Bastian Sept. 7, 2015 684 Declined
2
R best practices Daniel Himmelstein Aug. 29, 2015 1109 Open
3
Processing the DISEASES resource for disease–gene relationships Daniel Himmelstein Aug. 21, 2015 83 Completed
8
Processing DisGeNET for disease-gene relationships Daniel Himmelstein Aug. 20, 2015 153 Completed
4
Text as a resource for network population? Daniel Himmelstein Aug. 20, 2015 101 Accepted
3
Extracting side effects from SIDER 4 Daniel Himmelstein Aug. 11, 2015 188 Completed
7
Assessing the quality and applicability of the SIDER 2 resource Daniel Himmelstein Aug. 10, 2015 177 Completed
8
The TISSUES resource for the tissue-specificity of genes Daniel Himmelstein Aug. 9, 2015 125 Completed
4
Protein (target, carrier, transporter, and enzyme) interactions in DrugBank Daniel Himmelstein Aug. 5, 2015 992 Completed
3
Calculating molecular similarities between DrugBank compounds Daniel Himmelstein Aug. 4, 2015 239 Completed
16
Tissue Node Daniel Himmelstein Aug. 3, 2015 180 Completed
8
Compiling Gene Ontology annotations into an easy-to-use format Daniel Himmelstein July 29, 2015 351 Completed
1
Functional disease annotations for genes using DOAF Daniel Himmelstein July 14, 2015 86 Completed
1
Disease similarity from MEDLINE topic cooccurrence Daniel Himmelstein July 14, 2015 89 Completed
2
Extracting disease-gene associations from the GWAS Catalog Daniel Himmelstein July 9, 2015 305 Completed
3
Selecting informative ERC (evolutionary rate covariation) values between genes Daniel Himmelstein June 16, 2015 102 Completed
2
KaBOB Knowledgebase Daniel Himmelstein May 9, 2015 132 Declined
5
Unifying drug vocabularies Daniel Himmelstein May 5, 2015 429 Completed
3
Extracting indications from the ehrlink resource Daniel Himmelstein May 5, 2015 110 Completed
4
Retrieving the ingredients in RxNorm concepts Antoine Lizee May 1, 2015 680 Completed
4
Human Symptom Disease Network-MeSH ID Matching Daniel Himmelstein April 30, 2015 380 Completed
2
Mapping Incomplete Interactome disease names to MeSH Daniel Himmelstein April 29, 2015 72 Completed
5
Processing LabeledIn to extract indications Daniel Himmelstein April 8, 2015 144 Completed
9
Enabling reproducibility and reuse Daniel Himmelstein March 20, 2015 138 Open
2
MEDI indications data — discrepancy in resource-specific counts Daniel Himmelstein Feb. 17, 2015 109 Completed
5
Seeking an open source implementation of the Gerstein-Sonnhammer-Chothia Algorithm Antoine Lizee Jan. 26, 2015 183 Completed